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The medicine should not be used in combination with eletriptan, almotriptan or rizatriptan. It should also not be used if you have a liver disease, kidney disease or seizure disorder. Sumatriptan is the main ingredient of this drug. You should not take this medicine if you are allergic to this substance. The effects of this drug on the unborn baby are not known, therefore consult your doctor before taking this medicine if you are pregnant. It is also to be noted that brand or generic Imitrex should not be administered to patients below the age of 18. The medicine is also not advisable if you are over the age of 65 years.

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