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If in addition to Donepezil non-steroidal anti-inflammatory drugs NSAIDs such as aspirin, Ibuprofen, Diclofenac to be taken regularly, possibly increasing the risk of gastrointestinal bleeding. Children and adolescents as well as pregnant and nursing mothers should not take Donepezil, as no studies on the safety and efficacy of revenue. Also, patients should not with severe hepatic dysfunction due to lack of experience are taking Donepezil. Since when Donepezil is known? The development of Donepezil began in 1983 with the Japanese pharmaceutical company Eisai.
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