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Store your medicines at room temperature. Do not share this medication with others even if they have the same pathology as you. If you miss a dose, adapt to the next tablet. That is, if it has been a short time since you missed it, take it. However, if it has been a long time and the next tablet is next, you had better wait. In case of symptoms such as tremors, cramps, chest pain, anxiety attack, palpitations or other abnormal reactions, consult your doctor quickly or go to the nearest emergency service. Monitoring It is difficult to administer this type of hormones to any patient, it is necessary to control the dose and time of use; therefore, your doctor will indicate several tests at certain times.

The purpose is to know if the drug is keeping effect, and if not, determine whether it is due to the dose, absorption, failure of doses, drug interactions or multiple other causes. In principle, it should be weekly until we reach the stable value, then at 6-8 weeks and then at least every 3 months during the first year. Subsequently, your doctor will indicate this type of tests at least once a year, with any thyroid echo or other studies he considers important. As pediatric patients always deserve a delicate control, we have to use more than a TSH serum quantification, and in order to do it, we have to measure the levels of T4.

At least during the first week, the control should be exhaustive, not only on the dose but also on the proper compliance of the medication. Later, we will carry the same type of tests at similar intervals to those of the adult, up to the annual tests. Adverse Effects Side effects related to the use of this drug are like symptoms of hyperthyroidism since they usually occur from overdosing or from multiple doses. Among them, we have: Central nervous system: At first, we have some unspecific symptoms such as a headache, and then we see others of hyperthyroidism like nervousness and irritability, as well as emotional instability and anxiety attacks.

We rarely talk about seizures when it comes to this medication, even when the possibility exists. Palpitations are the most commented symptom; however, we can have others complications like the myocardial infarction, arrhythmias, anginas of chest angina, cardiac arrest, etc. This is why we must be careful using Levothyroxine in patients with cardiovascular problems, not only can we increase and aggravate these basic problems, but we can seriously affect the life of the patient. It is probable that there are hepatic disorders caused by the excess of the metabolism of this hormone, however, it is not very frequent. Alopecia and cutaneous rash. Weight loss is not only due to alterations in fat or muscle metabolism, but also due to disorders that occur at the bone level.

Density is a crucial factor affected in hyperthyroid processes, therefore, it is necessary to safeguard the doses and maintain constant control. It is necessary to emphasize that these disorders are temporary and do not cause long-term alterations. In the same way, we can observe alterations of the menstrual cycle in women. Special Considerations about Using Synthroid Pregnancy: Based on many studies carried out by specialists from various countries, we can safely state that Levothyroxine use is not dangerous during pregnancy. There are no reports of increases in the mortality rate or major congenital defects due to the use of this drug.

However, during pregnancy TSH levels increase, so it is necessary for your doctor to adjust the dose of Synthroid and constantly evaluate the levels of TSH in your blood. You do not need to discontinue or abandon your treatment; in fact, it can create major disruptions in your baby if you do. There are a small number of studies focused on the effect of Levothyroxine in breast milk. It is possible to find tiny amounts of Synthroid, however, there is not enough data to corroborate that it harms the baby in any way.

Treatment with the proper doses of this drug in the mother facilitates the secretion of breast milk. It is necessary that your doctor prescribe the exact doses, and seek to avoid any possible adverse effects that affect the baby. Geriatric patients: Since the alterations caused by Levothyroxine are lethal, especially cardiovascular complications, it is necessary to use very small doses in older patients. Atrial arrhythmias are quite frequent in this type of patients, so it is necessary to take special care. Losing Control of Your Metabolism All humans have a small gland of approximately 5 centimeters in diameter in our neck called Thyroid.

This small organism regulates the speed of most metabolic processes through two hormones: T3 and T4. In our body, there are metabolic reactions everywhere and almost at all times, therefore, so if there is an imbalance that alters these hormones, it is likely to affect almost all systems. In addition, Thyroid processes involve important connections with other glands such as the pituitary gland and regulatory centers such as the hypothalamus. In hypothyroidism, we have alteration in the thyroid that does not allow it to function properly, so the levels of T3 and T4 decrease and we see the decline of metabolic processes.

Depending on the specific cause, it can be a fast or slow process, compensated by the increase in TSH, also called thyrotropin, the hormone in charge of stimulating the thyroid to increase T3 and T4 production. In this way, TSH puts the thyroid to work to the maximum to compensate for the hormonal loss, however, it has a limit and that is where real hypothyroidism begins. In fact, many years ago there were epidemics of hypothyroidism related to people feeding. Iodine is a basic and fundamental primary resource for T3 and T4 formation, without it, people would have symptoms of hypothyroidism.

After these events, they added small amounts of iodine to the conventional salt so that people would consume this valuable mineral daily and avoid this type of hypothyroidism. We will list the most important causes: Autoimmune diseases: Related to alterations of the immune system or viral infections that cause primary lesions. Although it is not frequent, it is the most common endocrine alteration in newborns. In this case, mothers do not consume enough iodine during pregnancy, which triggers the disorder in the baby. Some antiarrhythmics and antidepressants. Iodine deficiency Radioactive disorders: Radiation therapy is a delicate process that can lead to other complicated lesions, especially in the thyroid.

These mutations are acquired during life and are less likely to be inherited. They are present only in tumor cells and are not transmitted to the children of the patient. Acquired changes in other oncogenes and tumor suppressor genes for example, ras, trk, gsp, p53 also play a role in the occurrence of papillary and follicular thyroid cancer. Mutations in patients with medullary thyroid carcinoma involve other parts of the RET gene compared with papillary carcinoma. Almost all patients with an inherited form of medullary thyroid cancer in 1 of 5 cases of sporadic forms of the same cancer have a mutation in the RET gene.

Most patients with sporadic medullary thyroid cancer have acquired mutations that are present only in their tumor cells. Patients with familial medullary cancer inherit a mutation of the RET gene from the parent. These mutations are present in every cell of the body and can be detected by examining the DNA of blood cells. Risk factors for thyroid cancer A risk factor is what increases the likelihood of developing cancer. For example, the intense exposure of the sun to the skin is a risk factor for skin cancer. Smoking is a risk factor for tumors of the lungs, mouth, larynx, bladder, kidneys and some other organs. However, the presence of one or several risk factors does not mean that a person will definitely develop cancer.

To date, there are several factors that increase the likelihood of thyroid cancer. However, most patients with thyroid cancer have no obvious risk factors. In addition, many people with one or more risk factors do not develop thyroid cancer at all. If a person has one or more risk factors, it is impossible to conclude how a certain factor affects the occurrence of cancer. Low iodine content in food Papillary and follicular thyroid cancer is more common in areas of the world where there is a low iodine content in foods. In some countries, iodine is specifically added to food salt and other foods. Radiation A proven risk factor for papillary thyroid cancer is irradiation of the head and neck in childhood.

In the past, children were exposed to acne, a fungal infection of the scalp, an enlarged thymus gland and to reduce the size of the tonsils or adenoids. After a few years, this type of treatment was associated with an increased risk of developing thyroid cancer. Radiation exposure in adults is accompanied by a slight risk of developing thyroid cancer. A number of studies have shown that the increased risk of nodules in the thyroid gland and even cancer is associated with radioactive fallout during the testing of nuclear weapons or incidents at nuclear power plants. Thus, there has been an increase in cases of thyroid cancer among children near the Ukrainian city of Chernobyl, where in 1986 there was an explosion at a nuclear power plant.

At the same time, millions of people were exposed to radioactive fallout. Rescuers and people living near the scene of the incident also have an increased incidence of thyroid cancer, although they were already adults at the time of the accident. Hereditary conditions People with certain hereditary diseases also have an increased risk of developing thyroid cancer. Thus, Gardner syndrome and familial polyposis are associated with an increased risk of thyroid cancer. Gender and age Benign thyroid nodules occur more frequently in women than in men.

Most cases of papillary and follicular cancer are detected at the age of 30-50 years. Benign and malignant tumors of the thyroid gland can occur in people of all ages. Lifestyle risk factors Tobacco and alcohol are the main risk factors for most head and neck tumors, including tumors of the mouth, pharynx, and esophagus. On the other hand, it is not proven that these factors increase the risk of developing thyroid cancer. Is it possible to prevent the occurrence of thyroid cancer? The risk factors are not known in the majority of patients with thyroid cancer, therefore it is impossible to prevent the development of such a disease in the vast majority of people.

Some researchers believe that the increase in thyroid cancer can be explained by X-ray examinations of young children. This assumption has not been confirmed, however, if possible, x-rays should be avoided in children. Most familial cases of medullary thyroid cancer can be prevented by conducting genetic blood tests. If such a disease is detected in the family, the rest of the family members should be examined. If there are cases of medullary thyroid cancer in the family, the rest of the family should be seen by a doctor who has the latest genetic counseling and testing information.

If RET gene mutations have been identified associated with familial medullary thyroid cancer even if there are no obvious nodules in the gland and other symptoms of the disease , then an operation can be offered to prevent the occurrence of medullary thyroid cancer. The only way to prevent medullary thyroid cancer in the presence of RET gene mutations is to remove the entire gland. After surgery, it is necessary to carry out hormone replacement therapy. Is early detection of thyroid cancer possible? In many cases, thyroid cancer can be detected early. In fact, in most patients, cancer of this location is diagnosed in earlier stages, and therefore is treated more effectively.

In rare cases, thyroid cancer is not accompanied by symptoms and therefore is detected in the later stages. Thyroid tumors are diagnosed early if the patient visits a doctor immediately after he has noticed it. Many tumors are detected during regular check-ups. If there are unusual symptoms in the form of a tumor nodule on the neck or neck swelling, you should immediately see a doctor. Some researchers recommend that the neck be self-examined twice a year to detect unusual formations or tumor nodes. People with a family of cases of medullary thyroid cancer have a very high risk of developing this type of cancer.

Removal of the thyroid gland in children in such families is an effective method of preventing this type of cancer, which can be fatal. If a patient refuses a genetic examination or operation to prevent medullary thyroid cancer, then there are other methods that can help identify the cancer at an early stage and provide effective treatment. Diagnosis of Thyroid Cancer Signs and symptoms of thyroid cancer Increased attention to signs and symptoms is the best way to early diagnose most thyroid cancers. With this type of cancer, the following signs and symptoms may appear: Compaction tumor formation on the neck, and sometimes fast-growing.

Pain in the neck, sometimes extending to the ear. Labored breathing. Cough not associated with an infectious disease. If any of these signs or symptoms appear, you should immediately consult a doctor. Other tumors of the neck and many non-neoplastic diseases can cause some of the above symptoms. However, the only way to find out if these symptoms are related to thyroid cancer is through a medical examination. The sooner the correct diagnosis is established, the faster the treatment will be initiated and the more effective it may be. Disease data and survey If there are signs or symptoms suspicious for thyroid cancer, then a full medical examination is necessary.

The doctor will ask about risk factors, symptoms and other health problems. If anyone in the family had thyroid cancer, especially medullary cancer, or pheochromocytoma - an adrenal tumor, you must inform your doctor. During the examination, the doctor will receive additional information about the signs and symptoms of thyroid cancer and health status. The doctor will pay special attention to the size and consistency of the thyroid gland and enlarged lymph nodes in the neck and will prescribe an additional examination. Research methods: Thyroid scan: During this study, a small amount of radioactive iodine or technetium is injected through the mouth or into a vein.

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All products are authentic brand names and will include a product information insert in English. Medical Information: Levotiron tablets contain the active ingredient levothyroxine sodium previously known simply as thyroxine sodium in the UK. Levothyroxine is also available without a brand name, ie as the generic medicine. Levothyroxine is the same as the hormone thyroxine, which is produced naturally by the thyroid gland. The thyroid gland produces and releases two thyroid hormones: Tri-iodothyronine is the more active thyroid hormone, and thyroxine is converted into T3 in various parts of the body. These hormones are responsible for maintaining a normal rate of metabolism in the body.

When the thyroid gland is unable to produce normal amounts of thyroxine, the level of both thyroid hormones in the blood decreases hypothyroidism. This results in a reduced rate of metabolism, leading to symptoms such as weight gain, intolerance to cold and tiredness. Levothyroxine tablets are given to replace the thyroxine that would normally be produced naturally by the thyroid gland. This returns levels of T3 and T4 to normal. Once the thyroid gland becomes unable to produce thyroxine, it will generally not return to normal function. This means that once thyroxine replacement is started, it usually needs to be taken for the rest of a person's life.

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Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Levothyroxine is used to treat an underactive thyroid hypothyroidism. If you notice other effects not listed above, contact your doctor or pharmacist. US residents can call their local poison control center at 1-800-222-1222.

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