Wash your hands before and after use. Do not wash your hands after use if putting this on your hand. Clean affected part before use. Make sure to dry well. Put a thin layer on the affected skin and rub in gently. Do not use coverings bandages, dressings unless told to do so by the doctor. If using on the groin, use a little bit. Do not wear tight clothing. Do not use diapers or plastic pants. What do I do if I miss a dose? Put on a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
Do not put on 2 doses at the same time or extra doses. See also: Lotrisone dosage information in more detail What are some side effects that I need to call my doctor about right away? Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit. Signs of Cushing's disease like weight gain in the upper back or belly, moon face, very bad headache , or slow healing. Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss. Skin changes pimples , stretch marks, slow healing, hair growth.
Change in color of skin. Thinning of the skin. Irritation where Lotrisone betamethasone and clotrimazole cream is used. Change in eyesight. What are some other side effects of Lotrisone? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Skin tingling. Avoid use of Lotrisone cream in the treatment of diaper dermatitis. Geriatric Use Clinical studies of Lotrisone cream did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.
However, greater sensitivity of some older individuals cannot be ruled out. The use of Lotrisone cream under occlusion, such as in diaper dermatitis, is not recommended. Postmarket adverse event reporting for Lotrisone cream in patients aged 65 and above includes reports of skin atrophy and rare reports of skin ulceration. Caution should be exercised with the use of these corticosteroid-containing topical products on thinning skin. Clotrimazole is an odorless, white crystalline powder, insoluble in water and soluble in ethanol. Betamethasone dipropionate is a white to creamy-white, odorless crystalline powder, insoluble in water.
Each gram of Lotrisone cream contains 10 mg clotrimazole and 0. Betamethasone dipropionate is a corticosteroid. Corticosteroids play a role in cellular signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action for the treatment of tinea pedis, tinea cruris and tinea corporis is unknown. Pharmacodynamics Vasoconstrictor Assay: However, similar blanching scores do not necessarily imply therapeutic equivalence. Pharmacokinetics Skin penetration and systemic absorption of clotrimazole and betamethasone dipropionate following topical application of Lotrisone cream has not been studied. The extent of percutaneous absorption of topical corticosteroids is determined by many factors, including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
Topical corticosteroids can be absorbed from normal intact skin. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids [see Dosage and Administration 2 ]. Once absorbed through the skin, the pharmacokinetics of topical corticosteroids are similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile. Microbiology Mechanism of Action: The methylsterols may affect the electron transport system, thereby inhibiting growth of fungi.
Activity In Vitro and In Vivo: Clotrimazole has been shown to be active against most strains of the following dermatophytes, both in vitro and in clinical infections, Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum [see Indications and Usage 1 ]. Drug Resistance: Strains of dermatophytes having a natural resistance to clotrimazole have not been reported. Resistance to azoles, including clotrimazole, has been reported in some Candida species. No single-step or multiple-step resistance to clotrimazole has developed during successive passages of Trichophyton mentagrophytes. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment of Fertility There are no adequate laboratory animal studies with either the combination of clotrimazole and betamethasone dipropionate or with either component individually to evaluate carcinogenesis.
It was positive in the in vitro human lymphocyte chromosome aberration assay, and equivocal in the in vivo mouse bone marrow micronucleus assay. Reproductive studies with betamethasone dipropionate carried out in rabbits at doses of 1. These doses are approximately 5- and 38-fold the maximum human dose based on body surface areas, respectively. No adverse effects on the duration of estrous cycle, fertility, or duration of pregnancy were noted. Clinical Studies In clinical trials of tinea corporis, tinea cruris, and tinea pedis, subjects treated with Lotrisone cream showed a better clinical response at the first return visit than subjects treated with clotrimazole cream. In tinea corporis and tinea cruris, the subject returned 3 to 5 days after starting treatment, and in tinea pedis, after 1 week.
Mycological cure rates observed in subjects treated with Lotrisone cream were as good as, or better than, in those subjects treated with clotrimazole cream. Use Lotrisone exactly as directed. Gently massage sufficient Lotrisone cream into the affected and surrounding skin areas twice a day, in the morning and evening. Treatment for 2 weeks on the groin or on the body and for 4 weeks on the feet is recommended. Precautions Tell your doctor before using Lotrisone, if you are pregnant or breast-feeding. Ingredients Active ingredients: Great medication to treat such problems.
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Use Lotrisone exactly as directed. Gently massage sufficient Lotrisone cream into the affected and surrounding skin areas twice a day, in the morning and evening. Treatment for 2 weeks on the groin or on the body and for 4 weeks on the feet is recommended. Precautions Tell your doctor before using Lotrisone, if you are pregnant or breast-feeding. Ingredients Active ingredients: Great medication to treat such problems. It is unmatched when it comes to reducing itching, redness and other symptoms of fungal infections. I know that fungus is not the worst problem people have after they return from the Middle East but still it is very unpleasant.
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Storage Room tenperature between 59-77 F 15-25 C. Store away from moisture and light. Keep Lotrisone Cream out of the reach of children and pets. Note The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes.
Lotrisone cream contains a mix of betamethasone as well as clotrimazol. Betamethasone is steroid that minimizes itching, swelling, as well as redness of the skin. Clotrimazole is an antifungal medicine that deals with infections brought on by fungi. Big Pharmacy offer to buy Lotrisone Online at low price. Betamethasone and Clotrimazole cream contains a combination of betamethasone and clotrimazol. Betamethasone is steroid that reduces itching, swelling, and redness of the skin. Clotrimazole is an antifungal medication that fights infections Cheap Lotrisone (Generic) without prescription. 2/8/ · Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Lotrisone (betamethasone and clotrimazole cream) with all of your drugs and health problems.