High blood sugar: Olanzapine, in rare instances, may cause an increase in blood sugar levels. Your doctor will monitor you if you have diabetes or are at risk of developing diabetes. If you experience weakness, increased thirst, increased urination, and increased appetite while taking this medication, contact your doctor. Liver disease: Olanzapine can affect liver function and cause liver problems. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Your doctor may want to test your liver function regularly with blood tests while you are taking this medication. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. Low blood pressure: Olanzapine may cause low blood pressure, especially when moving from a lying or sitting position to a standing position. If you have heart disease, cerebrovascular disease, or conditions that increase the risk of developing low blood pressure e.
Neuroleptic malignant syndrome NMS: Olanzapine, like other antipsychotic medications, can cause a potentially fatal syndrome known as neuroleptic malignant syndrome NMS. If you notice the symptoms of NMS such as high fever, confusion or loss of consciousness, racing or irregular heartbeat, muscle stiffness, or sweating, get immediate medical attention. Other medical conditions: If you have other medical conditions such as enlarged prostate glands, narrow-angle glaucoma, or paralytic ileus, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Prolonged erection: In rare cases, use of this medication by some men may cause them to develop priapism a prolonged and painful erection. If you have an erection that lasts for more than 4 hours, contact your doctor. Olanzapine may increase the risk of seizures, especially if you have had seizures in the past. If you are at risk of seizures and take this medication, you should be closely monitored by your doctor. Tardive dyskinesia TD: TD, a syndrome consisting of potentially irreversible, involuntary, repetitive movements of the face and tongue muscles, may develop in people who take certain antipsychotic medications including olanzapine. Although TD appears most commonly in seniors, especially women, it is impossible to predict who will develop TD.
Although the causes of death were varied, most of the deaths appeared to be either cardiovascular e. Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic s of the patients is not clear. Zyprexa olanzapine is not approved for the treatment of patients with dementia-related psychosis [see Warnings and Precautions 5. When using Zyprexa and fluoxetine in combination, also refer to the Boxed Warning section of the package insert for Symbyax.
Indications and Usage for Zyprexa See also: Ingrezza Schizophrenia Oral Zyprexa is indicated for the treatment of schizophrenia. Efficacy was established in three clinical trials in adult patients with schizophrenia: In adolescent patients with schizophrenia ages 13-17 , efficacy was established in one 6-week trial [see Clinical Studies 14. When deciding among the alternative treatments available for adolescents, clinicians should consider the increased potential in adolescents as compared with adults for weight gain and dyslipidemia. Clinicians should consider the potential long-term risks when prescribing to adolescents, and in many cases this may lead them to consider prescribing other drugs first in adolescents [see Warnings and Precautions 5.
Efficacy was established in three clinical trials in adult patients with manic or mixed episodes of bipolar I disorder: Efficacy was established in two 6-week clinical trials in adults. The effectiveness of adjunctive therapy for longer-term use has not been systematically evaluated in controlled trials [see Clinical Studies 14. Zyprexa IntraMuscular: Efficacy was demonstrated in 3 short-term 24 hours of IM treatment placebo-controlled trials in agitated adult inpatients with: Zyprexa and Fluoxetine in Combination: When using Zyprexa and fluoxetine in combination, refer to the Clinical Studies section of the package insert for Symbyax. Treatment Resistant Depression Oral Zyprexa and fluoxetine in combination is indicated for the treatment of treatment resistant depression major depressive disorder in patients who do not respond to 2 separate trials of different antidepressants of adequate dose and duration in the current episode , based on clinical studies in adult patients.
Zyprexa monotherapy is not indicated for the treatment of treatment resistant depression. Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week, since steady state for olanzapine would not be achieved for approximately 1 week in the typical patient. When indicated, dose escalation should be performed with caution in these patients. The physician who elects to use Zyprexa for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient.
Adolescents Dose Selection — Oral olanzapine should be administered on a once-a-day schedule without regard to meals with a recommended starting dose of 2.
For the maintenance treatment of bipolar disorder, the dose ranges from 5 mg to 20 mg daily. The tablets should be swallowed whole with a full glass of water and can be taken with or without food. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. you should know that olanzapine may cause fast or slow heartbeat, dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking olanzapine. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up. Zyprexa is the brand name of olanzapine, a prescription drug used to treat schizophrenia and bipolar www.kblkradio.com's also used to treat depression when used with other medications.. Zyprexa is part.
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If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately. Low blood pressure: Olanzapine may cause low blood pressure, especially when moving from a lying or sitting position to a standing position. If you have heart disease, cerebrovascular disease, or conditions that increase the risk of developing low blood pressure e. Neuroleptic malignant syndrome NMS: Olanzapine, like other antipsychotic medications, can cause a potentially fatal syndrome known as neuroleptic malignant syndrome NMS.
If you notice the symptoms of NMS such as high fever, confusion or loss of consciousness, racing or irregular heartbeat, muscle stiffness, or sweating, get immediate medical attention. Other medical conditions: If you have other medical conditions such as enlarged prostate glands, narrow-angle glaucoma, or paralytic ileus, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Prolonged erection: In rare cases, use of this medication by some men may cause them to develop priapism a prolonged and painful erection.
If you have an erection that lasts for more than 4 hours, contact your doctor. Zyprexa has been reported to cause weight gain, increased triglyceride and cholesterol levels, and increased blood sugar levels. Studies have shown that diabetes can develop in patients taking Zyprexa. Patients receiving Zyprexa should be monitored for elevated cholesterol, triglyceride, and blood sugar levels. In addition, patients should be aware of symptoms of high blood sugar levels including increased thirst, increased urination, and weakness. Antipsychotic agents have been reported to disrupt the body's ability to reduce core body temperature. Zyprexa should be used cautiously in patients who exercise strenuously or become dehydrated easily.
Zyprexa may make low blood pressure worse, leading to increased heart rate. It is also possible for heart rhythm changes to occur while taking Zyprexa. Lastly, Zyprexa is less likely than the typical antipsychotics to cause movement disorders similar to Parkinson. My eight year old daughter is taking Zyprexa 5mgs at night time daily. She had put on 30 pounds so the doctor took her off. Her anxiety and behavior got so awful we had to put her on it again. The doctor says she will get diabetes from this medicine and is telling me we will have to put her on something else called metformin. I hate to have her on any medication, however, she can't seem to function without this and we have tried others to no avail.
She has severe sensory issues and can only eat a limited variety of foods so I cannot give her "good diet foods" no matter how hard I try. Is she destined to get diabetes? Is it necessary to put her on the metformin? Will she get diabetes for sure if she doesnt take it? Zyprexa olanzapine is an antipsychotic medication used in the treatment of various psychoses and behavioral or mood disorders. The most common side effects with Zyprexa are drowsiness, weight gain, nausea, dry mouth, constipation, and dizziness. Other side effects of Zyprexa include hyperglycemia and diabetes.
Frequent side effects seen with metformin include diarrhea, nausea and vomiting, flatulence passing gas , abdominal discomfort stomach pain , headache, and weight loss. Other side effects with metformin are taste disturbance, and a decreased level of vitamin B12 in the bloodstream. No drug interactions between Zyprexa and metformin have been reported. This is not a complete list of the side effects associated with Zyprexa and metformin. Gregory Latham, RPh Q: What is the new drug being used to treat bipolar disorder with psychotic features, which is given as a monthly shot? My son had the Consta shot in the past, but now he is on another medicaton. It starts with an "S" and may be sycrest or stelazine.
He had his first shot today and will have another one in two weeks. Then he will get the shot monthly. The extended-release injectable suspension is approved for the treatment of schizophrenia in adults. Zyprexa oral products are approved for the treatment of acute mixed mania episodes associated with bipolar I disorder and for maintenance treatment of bipolar disorder. Zyprexa oral products are also approved for other medical conditions. Zyprexa Relprevv can be dosed every two weeks or every four weeks depending upon the dosage. Continue to take olanzapine even if you feel well. Do not stop taking olanzapine without talking to your doctor. Your doctor will probably want to decrease your dose gradually.
Other uses for this medicine This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. What special precautions should I follow? Before taking olanzapine, tell your doctor and pharmacist if you are allergic to olanzapine or any other medications. Be sure to mention any of the following: Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Tell your doctor if you have severe vomiting or diarrhea or signs of dehydration now, or if you develop these symptoms at any time during your treatment.
Also tell your doctor if you have ever had to stop taking a medication for mental illness because of severe side effects. If you become pregnant while taking olanzapine, call your doctor. Olanzapine may cause problems in newborns following delivery if it is taken during the last months of pregnancy. Do not drive a car or operate machinery until you know how this medication affects you. Do not drink alcohol while taking olanzapine. Talk to your doctor before using this form of olanzapine if you have phenylketonuria PKU. How should I take Zyprexa? Take Zyprexa exactly as prescribed by your doctor. Follow all directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Zyprexa can be taken with or without food. Zyprexa is usually taken once a day. Olanzapine may be only part of a complete program of treatment that also includes counseling and other psychological support programs. Follow your doctor's instructions. To take olanzapine orally disintegrating tablet Zyprexa Zydis: Keep the tablet in its blister pack until you are ready to take it. Open the package and peel back the foil from the tablet blister.
Do not push a tablet through the foil or you may damage the tablet. Using dry hands, place it in your mouth. It will begin to dissolve right away. Do not swallow the tablet whole.
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